Environmental Influences on Prenatal Development

Similarly, new proposals relative to vaccination with modified live viruses, such as those which have been devised by Koprowski and Sabin, although still in the research phase, receive a good review of the situation up to that date. A third new subject, which has actually only come into being in the last four or five years, is found in the papers dealing with the whole new family of enteric siruses-a family to which polioviruses have now been assigned. New relationships have been discovered between the behaviour of these viruses, and the infections they cause, and the behaviour of polioviruses. From the clinical standpoint there is also an excellent critique of newer diagnostic tests-neutralization, complement fixing, and precipitin tests. When one realizes that four years ago laboratory tests for the clinical diagnosis of poliomyelitis on the basis of the immunological response by the patient were rarely performed, the record of the present widespread use of these tests in the diagnostic laboratory is indeed impressive. Also, on the clinical and therapeutic side problems of respiratory distress in patients with life-threatening poliomyelitis receives detailed attention. No one who wishes to remain abreast of the rapidly moving field of poliomyelitis can afford to be without this book, and, if he is historically minded, he should also try to secure some of the previous volumes in this